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Skin Care for Wrinkle and Aging


Registered on 2012. 10. 15

Background

Aging comes along and brings baggage in the form of wrinkles. Some are not preventable while others are. Facial wrinkles appear without any warning. The most common reasons are aging, environmental damage, loss of moisture and impaired new cell growth. Repetitive movements of facial muscles such as frowning, squinting, and even smiling can drastically speed up the wrinkle process. There are 3 types of wrinkles. Anti-aging treatments, from holistic home prevention methods to clinical injections at a medical spa and of course, drastic surgical solutions from plastic surgery have become a national pastime. In the 21st century, adults (and even many teens) are obsessed with outer beauty, and how to slow the clock on the physical aging process. Truly, no one can prevent aging but understanding the different types of wrinkles and what causes each kind can be a good starting point to slowing the clock a little. Though they are all unsightly, troublesome and unwanted, wrinkles actually come in three different types – dynamic, static and folds. Knowing the differences between them is essential for deciding how to treat facial wrinkles, and possibly prevent or delay the formation of new wrinkles.

 

 

Dynamic Wrinkles

The first type of wrinkles is called a dynamic wrinkle, which is most commonly caused by repeatedly contracting muscles through facial expressions. Muscle contractions make lines between the muscles, causing dynamic wrinkles to form. A few common examples:

         Frowning or furrowing the brow contracts certain muscles that create those deep          wrinkle lines between the eyebrows.

         Raising of the eyebrows contracts muscles that, over time, etch those horizontal           wrinkle lines across the forehead.

         Smiling and squinting bunch the skin on the cheeks and near the outer corners of        the eyes, making the wrinkled lines we commonly refer to as crow’s feet.

 

 

Static Wrinkles

The second type is known as static wrinkles, which come from the loss of elasticity due to age and lifestyle. Smoking, sun exposure, poor nutrition, or prolonged dynamic wrinkling can all cause static wrinkles. Heredity plays a part in the formation of static wrinkles also. Static wrinkles are always visible and do not require contractions to be seen the way a dynamic wrinkle does. Unfortunately, over time, most dynamic wrinkles become static wrinkles and are visible all the time. A few common examples of static wrinkles:

         The crepe-ish look around the eyes that usually begins in the mid 30s and         continues to progress with age.

         That crosshatched appearance of the skin around the cheek areas that starts to show up in the late 30s and gets progressively more pronounced with age.

 

 

Wrinkle Folds

The third type of wrinkles has been referred to as wrinkle folds. In most cases, wrinkle folds are caused by the loss of subcutaneous facial fat and sagging of the underlying facial structures. This is truly the most common type of wrinkles from the natural progression of age. The most common one that people can relate to.

 

 

Treatment of Wrinkle

Although no one can stop the clock and turn back the aging process, there are many things that can be done to slow down the process. Preventative measures such as leading a healthy lifestyle, taking care of the skin over a lifetime, and trying to lead a life that is as stress free as possible.

 

 

Why Choose Our Product

Until recently there hasn't been any real viable anti-wrinkle solutions pertaining to repetitive facial movements besides BOTOX® – which paralyzes the facial muscles. We have discovered a unique BEP that can reduce the muscle contractions and diminishes the depth and length of facial wrinkles. Our BEP offers the same results as BOTOX® without needles or the risk of damage to the skin or facial muscles. In 70 human subjects (an average age of 48.2 years), this BEP was able to decrease skin roughness as a measure for wrinkles. Subsequent molecular analysis further illustrated the effectiveness of this novel BEP in boosting extracellular matrix formation. Our BEP formulation produces a significant reduction in both the depth and size of wrinkles and fine lines. BOTOX® actually paralyzes muscles so that they can't contract. Our BEP formulation is non-invasive and safe for use in all areas of the face and throat (unlike BOTOX®), and provides continuous, cumulative effects, which can ultimately last longer than BOTOX®.

 

 

Experimental validation of our novel BEP product

An in silico approach was used to identify this novel BEP. We validated the effectiveness of this novel peptide. As a proof-of-principle study, our novel BEP as assessed for its effects on the protein production of key components of extracellular matric.  Protein expression of pro-collagen I, hyaluronic acid and fibronectin on skin was significantly increased in 10 healthy human volunteers as compared to placebo controls (Figure 1).  In addition, effects of novel BEP on facial wrinkle were further assessed in 30 subjects (Figure 2).

 

 










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