comes along and brings baggage in the form of wrinkles. Some are not
preventable while others are. Facial wrinkles appear without any warning. The
most common reasons are aging, environmental damage, loss of moisture and
impaired new cell growth. Repetitive movements of facial muscles such as
frowning, squinting, and even smiling can drastically speed up the wrinkle
process. There are 3 types of wrinkles. Anti-aging
treatments, from holistic home prevention methods to clinical injections at a
medical spa and of course, drastic surgical solutions from plastic surgery have
become a national pastime. In the 21st century, adults (and even many teens)
are obsessed with outer beauty, and how to slow the clock on the physical aging
process. Truly, no one can prevent aging but understanding the different types
of wrinkles and what causes each kind can be a good starting point to slowing
the clock a little. Though they are all unsightly, troublesome and unwanted,
wrinkles actually come in three different types – dynamic, static and folds.
Knowing the differences between them is essential for deciding how to treat facial
wrinkles, and possibly prevent or delay the formation of new wrinkles.
The first type of
wrinkles is called a dynamic wrinkle, which is most commonly caused by
repeatedly contracting muscles through facial expressions. Muscle contractions
make lines between the muscles, causing dynamic wrinkles to form. A few common
furrowing the brow contracts certain muscles that create those deep wrinkle lines between the eyebrows.
Raising of the
eyebrows contracts muscles that, over time, etch those horizontal wrinkle lines across the forehead.
squinting bunch the skin on the cheeks and near the outer corners of the eyes, making the wrinkled lines we
commonly refer to as crow’s feet.
The second type is
known as static wrinkles, which come from the loss of elasticity due to age and
lifestyle. Smoking, sun exposure, poor nutrition, or prolonged dynamic
wrinkling can all cause static wrinkles. Heredity plays a part in the formation
of static wrinkles also. Static wrinkles are always visible and do not require
contractions to be seen the way a dynamic wrinkle does. Unfortunately, over
time, most dynamic wrinkles become static wrinkles and are visible all the
time. A few common examples of static wrinkles:
look around the eyes that usually begins in the mid 30s and continues to progress with age.
crosshatched appearance of the skin around the cheek areas that starts to show up
in the late 30s and gets progressively more pronounced with age.
The third type of
wrinkles has been referred to as wrinkle folds. In most cases, wrinkle folds
are caused by the loss of subcutaneous facial fat and sagging of the underlying
facial structures. This is truly the most common type of wrinkles from the
natural progression of age. The most common one that people can relate to.
Although no one can
stop the clock and turn back the aging process, there are many things that can
be done to slow down the process. Preventative measures such as leading a
healthy lifestyle, taking care of the skin over a lifetime, and trying to lead
a life that is as stress free as possible.
Why Choose Our
recently there hasn't been any real viable anti-wrinkle solutions pertaining to
repetitive facial movements besides BOTOX® – which paralyzes the facial
muscles. We have discovered a unique BEP that can reduce the muscle
contractions and diminishes the depth and length of facial wrinkles. Our BEP
offers the same results as BOTOX® without needles or the risk of damage to the
skin or facial muscles. In 70 human subjects (an average age of 48.2 years),
this BEP was able to decrease skin roughness as a measure for wrinkles.
Subsequent molecular analysis further illustrated the effectiveness of this
novel BEP in boosting extracellular matrix formation. Our BEP formulation
produces a significant reduction in both the depth and size of wrinkles and
fine lines. BOTOX® actually paralyzes muscles so that they can't contract. Our
BEP formulation is non-invasive and safe for use in all areas of the face and
throat (unlike BOTOX®), and provides continuous, cumulative effects, which can
ultimately last longer than BOTOX®.
validation of our novel BEP product
An in silico
approach was used to identify this novel BEP. We validated the effectiveness of
this novel peptide. As a proof-of-principle study, our novel BEP as assessed
for its effects on the protein production of key components of extracellular
matric. Protein expression of pro-collagen
I, hyaluronic acid and fibronectin on skin was significantly increased in 10
healthy human volunteers as compared to placebo controls (Figure 1). In addition, effects of novel BEP on facial
wrinkle were further assessed in 30 subjects (Figure 2).