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Acne


Registered on 2012. 10. 15

What Causes Acne?

From the moment you are born, your skin begins a lifelong process of shedding dead cells and producing oil. This process can be disrupted by your hormone balance, which changes throughout your life. The acne cycle is initiated when excess oil and dead skin cells combine to plug the pore of a hair follicle; behind the plugged pore, bacteria grow and multiply, triggering inflammation and swelling. That's an acne blemish. All types of acne - blackheads, whiteheads, pimples, and cysts - develop when pores in our skin become clogged. The culprit is sebum, an oil in our skin. Our bodies make more sebum when our hormones surge. This is why teens get acne. This is why women often breakout before their periods. Since hormones fluctuate in the years leading up to menopause, many women in their 40s and 50s get acne.

 

Why do people get different types of acne?

What happens inside the clogged pore determines the type of acne we see. 

A blackhead appears when sebum and dead skin cells clog the pore. While the pore is clogged, its surface remains open. This lets us look into the pore and see a black color. A whitehead forms when the excess oil and dead skin cells clog the pore and block the opening of the pore. The excess oil does more than clog pores. Bacteria that normally live on our skin, Propionibacterium acnes (P. acnes), thrive in this excess oil. Immersed in excess oil, the bacteria can rapidly increase in number. As the bacteria multiply in a clogged pore, the pore becomes inflamed. Inflammation is what causes a pimple to look red, hot, and swollen. When inflammation reaches deep into the skin, an acne cyst forms. This is the most severe type of acne. Cysts can be very painful. People often see permanent scarring after this type of acne heals.

 

How to getting rid of acne?

Thanks to advances in medicine, today, most case of acne can be controlled. Many people with mild acne can see clear skin with good skin care and acne products available without a prescription. However, this won’t control everyone’s acne. Sometimes acne control requires a dermatologist’s help. Even severe acne can be successfully controlled with treatment from a dermatologist. While treating acne may seem unimportant, research shows treatment has value. Treating acne can prevent additional breakouts and scars. It can improve a person’s quality of life. People living with acne can suffer from low self-esteem, anxiety, and depression. Acne can even discourage people from pursuing life's dreams. When acne is under control, a person’s confidence grows. Anxiety and depression diminish.

 

Important role of Propionibacterium acnes

Propionibacterium acnes (P. acnes) is a relatively slow growing, typically aerotolerant anaerobic gram positive bacterium that is linked to the skin condition acne. This bacterium is largely commensal and part of the skin flora present on most healthy adult human skin. It is usually just barely detectable on the skin of healthy pre-adolescents. It lives primarily on, amongst other things, fatty acids in the sebaceous glands on sebum secreted by follicles. It may also be found throughout the gastrointestinal tract in humans and many other animals. It is named after its ability to generate propionic acid.

 

Role of Propionibacterium acnes in human skin disease

Acne vulgaris (commonly called acne) is a skin disease that is most common during adolescence, afflicting more than 80% of teenagers and over 40 million people in United States alone. Acne is inflammatory and associated with immune response to P. acnes. 

 

Myths about the causes of acne

Acne is not caused by anything you're "doing". Instead, acne is a complex condition triggered by genetics and hormones— sometimes aggravated by stress. Acne is surprisingly common. People with acne often feel incredibly alone but the fact is, acne is the most common skin disease in the world, with tens of millions of sufferers. More than 85% of Americans have acne breakouts at some time in their lives. Among teenagers, about 90% develop acne, and it can last all their teen years. Many adults have acne, too. Among adult women, about 50% experience acne breakouts at some point; among men, about 25%—and the chronic nature of the condition means adults may have to endure symptoms for decades if not treated with appropriate acne medication.

 

Learn more about adult acne - acne is chronic but treatable

Acne is what doctors call a chronic condition, which means it can last for years—even decades in adults. Because there is no cure, the key to a clear complexion is control and prevention with the kind of medicated daily maintenance therapy that our product provides. The pimples you see today started as tiny microcomedones, or pre-pimples, deep inside your skin about three weeks before breaking out. Hundreds of tiny pre-pimples may be forming continuously in any of the thousands of pores on your face. Even when your skin looks clear, they may still be there - percolating invisibly under the skin's surface. To help you get and maintain clear skin. Our product helps keep these pre-pimples from forming or emerging - and that's what it means to treat chronic acne proactively.

 

Why Choose Our Product

Antimicrobial agents and antibiotics have been commonly used to treat acne for several decades. However, several side effects have been reported including erythema, scaling, burning, and flare. Our product, a BEP cream, is safe and effective for mild to moderate acne - healing the breakouts you may have today. Our product may also help to keep blemishes from leaving behind permanent scars. Our product effectively kills acne-causing bacteria inside pores; and to soothe redness and irritation. Our BEP cream effectively inhibits the growth of P. acnes – the bacterium that promotes inflammatory acnes.  To increase its solubility, biomimetic peptide was incorporated into a liposome formulation to aid its delivery to P. acnes.  Our product holds great potential of becoming a safe and effective therapeutic medication for acne vulgaris and other P. acnes associated skin diseases.

 

 



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